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The Lee Auto Breech Lock Pro is a true progressive press for less than the cost of a premium single stage press. Order a set of Lee dies and a shell plate, and you have everything you need to start reloading. User has to make initial die adjustment into the Breech Lock bushings. Once set, the Breech Lock system allows for instant change. Lee Auto Breech lock Pro Shell plate is required to use this press, sold separately. Features: - Easy to use with no adjustments - Modular construction allows as much or as little automation as the operator desires with no adjustments - Cartridge changeover in seconds, including primer size with no adjustments - Breech Lock quick change feature in all four positions with no adjustments - Exclusive auto case placer with no adjustments - Through ram primer disposal with convenient built-in primer disposal tube Includes: - (4) breech lock bushings - Large and small priming arms - Ergonomic, wood grip roller handle - Hex wrenches for caliber changes with built in storage rack for tools Specifications: - Weight: 11. 05 lbs. - Press Type: Progressive Press - Priming Feature: Yes - Handle Location: Ambidextrous - Number of Mounting Holes: 3 - Spent Primer Collection System: Yes - Die Size Accepted: Standard 7/8"-14 Threaded Dies - Die Bushing Accepted: Yes - Frame Design: O-Frame - Die Bushing Brand Used: Lee
Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;